Hydrochloric Acid → N-(4-chlorobenzyl)urea

HRID 1108225ノート

反応式

HRID 1108225 の反応式
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[O-:10][C:11]#[N:12].[Na+].Cl>O>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH:7][C:11]([NH2:12])=[O:10])=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 660364-ChlorobenzylamineHCID 517096Sodium Cyanate2 回

生成物 1

HCID 1484508N-(4-chlorobenzyl)urea

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

100 ml of 95% 4-chlorobenzylamine and 51.53 g of sodium cyanate in 1 liter of water were treated below 25° C. with 194 ml of 4N HCl. Further sodium cyanate (5.15 g) was added and the pH adjusted to 7.3. After 3 days the solid was collected, washed with water and dried to give the title compound (131.1 g) as a white solid mp 186-9° C.

後処理

  1. customAfter 3 days the solid was collected
  2. washwashed with water
  3. customdried

出典と根拠

ORDレコード
ord-70f166a88b624bdfb7c42732610604fa
出典データセット
uspto-grants-2000_05
特許番号
US06066641

反応ノート

読み込み中…