2-(2-Formyl-6-methoxyphenoxy)acetaldehyde → 7-Methoxy-1-benzofuran-2-carbaldehyde

HRID 1108315ノート

反応式

HRID 1108315 の反応式
[CH:1]([C:3]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH3:14])[C:4]=1[O:5][CH2:6][CH:7]=[O:8])=O>C(O)(=O)C>[CH:7]([C:6]1[O:5][C:4]2[C:9]([O:13][CH3:14])=[CH:10][CH:11]=[CH:12][C:3]=2[CH:1]=1)=[O:8]

参加物

3

反応物 1

HCID 184236532-(2-Formyl-6-methoxyphenoxy)acetaldehyde

生成物 1

HCID 34573107-Methoxy-1-benzofuran-2-carbaldehyde

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

2-(2-Formyl-6-methoxyphenoxy)acetaldehyde, dimethyl acetal (31 g) was heated to reflux in glacial acetic acid (120 ml) overnight. The mixture was then cooled and the solvent removed in vacuo to give a red oil. Purification by Kugelrohr distillation gave the title compound (17 g) as a pale yellow oil which solidified on standing.

後処理

  1. temperatureThe mixture was then cooled
  2. customthe solvent removed in vacuo
  3. customto give a red oil
  4. customPurification
  5. distillationby Kugelrohr distillation

出典と根拠

ORDレコード
ord-d710e542c55b43fb8d79734520600a6b
出典データセット
uspto-grants-2000_05
特許番号
US06066657

反応ノート

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