2-Acetylpyridine → 1-[[[[1-(2-Pyridinyl)ethylidene]hydrazino]carbonyl]methyl]pyridinium chloride

反応式

[CH:1]1[CH:6]=[CH:5][N+:4]([CH2:7][C:8]([NH:10][NH2:11])=[O:9])=[CH:3][CH:2]=1.[Cl-:12].[C:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=1)(=O)[CH3:14]>>[Cl-:12].[N:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[C:13](=[N:11][NH:10][C:8]([CH2:7][N+:4]1[CH:3]=[CH:2][CH:1]=[CH:6][CH:5]=1)=[O:9])[CH3:14]

参加物

反応物 2

HCID 142862-Acetylpyridine

HCID 70773Pyridinioacetohydrazide chloride

生成物 1

HCID 738673101-[[[[1-(2-Pyridinyl)ethylidene]hydrazino]carbonyl]methyl]pyridinium chloride

実験手順

Following the general method of Example 2 and making non-critical variations, 5.63 gm (0.03 mole) of Girard's Reagent P and 3.63 gm (0.03 mole) of 2-acetylpyridine yield 5.70 gm (65%) of the title compound; mp 183.7° (decomp).

出典と根拠

ORDレコード: ord-1a59fc28191c46358605d52e488870da
出典データセット: uspto-grants-1990_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04978670

反応ノート

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