Bromine → HCID 86744381、化合物

HRID 1111148ノート

反応式

HRID 1111148 の反応式
[Br-:1].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6].BrBr>O>[Br-:1].[Br-:1].[Br-:1].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6]

参加物

4

反応物 2

HCID 24408BromineHCID 74724Choline Bromide

生成物 1

HCID 86744381HCID 86744381、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
50 °C

実験手順

The recrystallized N-(2-hydroxyethyl)-N,N,N-trimethylammonium bromide (55.86 grams, 0.30 moles) was placed in a 100 ml flask fitted with a magnetic stirrer and a pressure equalizing addition funnel. Water (29 ml) was added to make a 50% solution and the solution was stirred vigorously while 48.5 grams (0.30 moles) of bromine was added dropwise from the addition funnel. The tribromide fell out of solution as a dark red oil. The product was separated from the aqueous layer by decantation and the residual water removed by warming to 50° C. at aspirator pressure for fifteen minutes. The yield of N-(2-hydroxyethyl)-N,N,N-trimethylammonium tribromide was 103.16 grams. Analysis: %Brtot =67.63 (exp), 69.71 (theo); %Brox =44.10 (exp), 46.41 (theo).

後処理

  1. customfitted with a magnetic stirrer
  2. additionaddition funnel
  3. additionwas added dropwise from the addition funnel
  4. customThe product was separated from the aqueous layer by decantation
  5. customthe residual water removed

出典と根拠

ORDレコード
ord-96ea27723ce44e7fa4adb94a18aa2ed3
出典データセット
uspto-grants-1990_12
特許番号
US04978685

反応ノート

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