2-((4-Methyl-5-imidazolyl)methylthio)ethylthiourea → HCID 178433689、化合物

HRID 1112226ノート

反応式

HRID 1112226 の反応式
Cl[CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][C:10]=1[CH3:11].[CH3:12][C:13]1[NH:17][CH:16]=[N:15][C:14]=1[CH2:18][S:19][CH2:20][CH2:21][NH:22][C:23]([NH2:25])=[S:24]>C(O)C>[CH3:12][C:13]1[NH:17][CH:16]=[N:15][C:14]=1[CH2:18][S:19][CH2:20][CH2:21][NH:22][C:23](=[NH:25])[S:24][CH2:2][CH2:3][S:4][CH2:5][C:6]1[N:7]=[CH:8][NH:9][C:10]=1[CH3:11]

参加物

4

反応物 2

HCID 127186972-((4-Methyl-5-imidazolyl)methylthio)ethylthioureaHCID 132173604-{[(2-Chloroethyl)sulfanyl]methyl}-5-methyl-1H-imidazole

生成物 1

HCID 178433689HCID 178433689、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

1-Chloro-2-(5-methyl-4-imidazolylmethylthio)ethane and N-[2-(5-methyl-4-imidazolylmethylthio)ethyl]thiourea are heated together at reflux temperature in ethanol, and the mixture is evaporated and the residue purified to give the title compound, which may be converted into a suitable salt by ion-exchange chromatography.

後処理

  1. customthe mixture is evaporated
  2. customthe residue purified

出典と根拠

ORDレコード
ord-838f52272ad44abfba5820989740c17a
出典データセット
uspto-grants-1978_10
特許番号
US04120972

反応ノート

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