Ethyl cyanoformate → Pirolate

HRID 1112241ノート

反応式

HRID 1112241 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[C:8]([NH2:15])[C:7]([C:16]([NH2:18])=[O:17])=[CH:6]2.[C:19]([C:21]([O:23][CH2:24][CH3:25])=[O:22])#N>C1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[C:8]1[N:15]=[C:19]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[NH:18][C:16](=[O:17])[C:7]1=[CH:6]2

参加物

4

反応物 2

HCID 69336Ethyl cyanoformateHCID 7815842-Amino-6,7-dimethoxyquinoline-3-carboxamide

生成物 1

HCID 135445830Pirolate

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

Still further, a mixture of 6,7-dimethoxy-2-aminoquinoline-3-carboxamide (0.5 g., 2 millimoles), ethyl cyanoformate (0.43 g., 44 millimiles) and benzene (30 ml.) is refluxed for three days. The mixture is then cooled, filtered and the solid extracted with chloroform. Concentration of the chloroform extract affords the product which is recrystallized from chloroform.

後処理

  1. temperatureis refluxed for three days
  2. temperatureThe mixture is then cooled
  3. filtrationfiltered
  4. extractionthe solid extracted with chloroform
  5. extractionConcentration of the chloroform extract
  6. customaffords the product which
  7. customis recrystallized from chloroform

出典と根拠

ORDレコード
ord-dd5e7d5fefa5458a8f5c20ee8a84d550
出典データセット
uspto-grants-1978_10
特許番号
US04120962

反応ノート

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