4-Benzyl-2-(chloromethyl)morpholine → 4-Benzyl-2-(1-phenyl-2,3-dihydro-imidazo(4,5-b)pyridin-2-on-3-yl-methyl)-morpholine hydrochloride

関与物質

反応手順

The condensation of 0.1 mol of 1-phenyl-2,3-dihydroimidazo(4,5-b)pyridin-2-one and of 0.1 mol of 2-chloromethyl-4-benzyl-morpholine is carried out in accordance with the procedure of Example 1. Recrystallization of the product from a 50/25 mixture of ethyl acetate and isopropanol gives 19 g of 4-benzyl-2-(1-phenyl-2,3-dihydroimidazo (4,5-b)pyridin- 2-on-3-yl-methyl)-morpholine hydrochloride, m.p. 214° C.

情報源と証拠