4-Hydroxy-3,5-dinitrobenzaldehyde → HCID 22763893、化合物

HRID 1112382ノート

反応式

HRID 1112382 の反応式
FC(F)(F)C1NC2C([N+]([O-])=[O:13])=CC(C(F)(F)F)=CC=2N=1.[N+:21]([C:24]1[CH:29]=[C:28]([CH:30]([F:32])[F:31])[CH:27]=[C:26]([N+:33]([O-:35])=[O:34])[CH:25]=1)([O-:23])=[O:22].[N+](C1C=C(C=C([N+]([O-])=O)C=1O)C=O)([O-])=O>>[N+:21]([C:24]1[CH:29]=[C:28]([CH:30]([F:31])[F:32])[CH:27]=[C:26]([N+:33]([O-:35])=[O:34])[C:25]=1[OH:13])([O-:23])=[O:22]

参加物

4

反応物 3

HCID 1040914-Hydroxy-3,5-dinitrobenzaldehydeHCID 22763917HCID 22763917、化合物HCID 178526649HCID 178526649、化合物

生成物 1

HCID 22763893HCID 22763893、化合物

実験手順

Compounds in which the substituent in the 6(5) position of the benzene ring of the benzimidazole is difluoromethyl are prepared from 2,6-dinitro-4-difluoromethylbenzene according to the above procedure. This latter compound is prepared by the reaction of SF4 and 3,5-dinitro-4-hydroxybenzaldehyde to yield 2,6-dinitro-4-difluoromethylphenol which is converted to the corresponding chloride by conventional means. 2-Trifluoromethyl-4-nitro-6-difluoromethylbenzimidazole was prepared from the above diamine by the process of the above example and melted at about 132°-134° C. after recrystallization from benzene.

出典と根拠

ORDレコード
ord-71a54c7f266a4bdca8fd9ba0c68a4e60
出典データセット
uspto-grants-1978_10
特許番号
US04122184

反応ノート

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