alpha-Hydroxyacetophenone → 2-(N-Butylamino)-4-phenyloxazole

HRID 1112387

反応式

HRID 1112387 の反応式
[CH2:1]([OH:10])[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=O.[CH2:11]([NH:15][C:16]#[N:17])[CH2:12][CH2:13][CH3:14]>>[CH2:11]([NH:15][C:16]1[O:10][CH:1]=[C:2]([C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[N:17]=1)[CH2:12][CH2:13][CH3:14]

参加物

3

反応物 2

HCID 68490alpha-HydroxyacetophenoneHCID 12295218Butylcyanamide

生成物 1

HCID 122952382-(N-Butylamino)-4-phenyloxazole収率 47%

実験手順

The procedure as described in Example 1 was followed using phenacyl alcohol and butylcyanamide. A colourless oil was obtained after distillation of the product. Wt. = 5.0 g., 47% Yield. b.p. 134° C/0.1 mm., which crystallised on standing. The analytical sample which separated as needles from petrol (40°-60° C) had m.p. 52°-53° C.

後処理

  1. customA colourless oil was obtained
  2. distillationafter distillation of the product
  3. custom, which crystallised
  4. customThe analytical sample which separated as needles from petrol (40°-60° C)

出典と根拠

ORDレコード
ord-8852b30e462e458da452a7751c0dfa92
出典データセット
uspto-grants-1978_10
特許番号
US04122183

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