2-(7-amino-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-N,N-dimethylacetamide → 2-[5-Chloro-2-(3-dimethylcarbamoylmethyl-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino)-pyrimidin-4-ylamino]-5-methoxy-N-methyl-benzamide

反応式

[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH3:14])[cH:15][c:16]([O:19][CH3:20])[cH:17][cH:18]2)[n:7]1.[NH2:22][c:23]1[cH:24][c:25]2[c:26]([cH:38][c:39]1[O:40][CH3:41])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]([CH3:36])[CH3:37])[CH2:30][CH2:31]2>>[c:2]1([NH:22][c:23]2[cH:24][c:25]3[c:26]([cH:38][c:39]2[O:40][CH3:41])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]([CH3:36])[CH3:37])[CH2:30][CH2:31]3)[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH3:14])[cH:15][c:16]([O:19][CH3:20])[cH:17][cH:18]2)[n:7]1