Dichloromethane → tert-butyl N-[4-[[1-cyano-2-[4-(4-cyano-3-methylphenyl)phenyl]ethyl]carbamoyl]oxan-4-yl]carbamate

反応式

[Cl:38][CH2:39][Cl:40].[NH2:1][C:2]([CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]([CH3:19])[c:14]([C:17]#[N:18])[cH:15][cH:16]2)[cH:9][cH:10]1)[NH:20][C:21](=[O:22])[C:23]1([NH:29][C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:24][CH2:25][O:26][CH2:27][CH2:28]1)=[O:37]>>[N:1]#[C:2][CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]([CH3:19])[c:14]([C:17]#[N:18])[cH:15][cH:16]2)[cH:9][cH:10]1)[NH:20][C:21](=[O:22])[C:23]1([NH:29][C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:24][CH2:25][O:26][CH2:27][CH2:28]1

参加物

反応物 2

HCID 6344Dichloromethane

HCID 68429468tert-butyl N-[4-[[1-amino-3-[4-(4-cyano-3-methylphenyl)phenyl]-1-oxopropan-2-yl]carbamoyl]oxan-4-yl]carbamate

生成物 1

HCID 72328361tert-butyl N-[4-[[1-cyano-2-[4-(4-cyano-3-methylphenyl)phenyl]ethyl]carbamoyl]oxan-4-yl]carbamate

出典と根拠

ORDレコード: ord-a5ea534c2c87409e963e647efd7902aa
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…