Acetate → N-[3-fluoro-5-(1,3-thiazol-5-yl)phenyl]-4-(trifluoromethyl)pyrimidin-2-amine

反応式

[C:25](=[O:26])([O-:27])[O-:28].[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[Cl:14][c:15]1[n:16][cH:17][cH:18][c:19]([C:21]([F:22])([F:23])[F:24])[n:20]1.[Cs+:29].[Cs+:30].[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][c:7](-[c:9]2[cH:10][n:11][cH:12][s:13]2)[cH:8]1.[O-:38][C:39]([CH3:40])=[O:41].[O-:42][C:43]([CH3:44])=[O:45].[Pd+2:37]>>[F:1][c:2]1[cH:3][c:4]([NH:5][c:15]2[n:16][cH:17][cH:18][c:19]([C:21]([F:22])([F:23])[F:24])[n:20]2)[cH:6][c:7](-[c:9]2[cH:10][n:11][cH:12][s:13]2)[cH:8]1