Dimethylformamide → 2-{[6-Chloro-4-(chloromethyl)pyridin-2-yl]amino}-1,3-thiazole-5-carbonitrile

反応式

[CH3:18][N:19]([CH3:20])[CH:21]=[O:22].[Cl:1][c:2]1[cH:3][c:4]([CH2:16][OH:17])[cH:5][c:6]([NH:8][c:9]2[s:10][c:11]([C:14]#[N:15])[cH:12][n:13]2)[n:7]1.[Cl:28][CH2:29][Cl:30].[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:16][Cl:25])[cH:5][c:6]([NH:8][c:9]2[s:10][c:11]([C:14]#[N:15])[cH:12][n:13]2)[n:7]1