Diethyl Ether → [3-(4-Iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]methanol

反応式

[BH4-:21].[CH2:23]([O:24][CH2:25][CH3:26])[CH3:27].[I:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([C:17](=[O:18])[O:19][CH3:20])[CH:10]3[CH2:11][CH2:12][CH:13]([CH2:14]2)[N:15]3[CH3:16])[cH:6][cH:7]1.[Li+:22]>>[I:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([CH2:17][OH:18])[CH:10]3[CH2:11][CH2:12][CH:13]([CH2:14]2)[N:15]3[CH3:16])[cH:6][cH:7]1