Dichloromethane → oxolan-3-yl N-[1-[6-fluoro-2-(2-hydroxyphenyl)quinazolin-4-yl]pyrrolidin-3-yl]carbamate

反応式

[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[Cl:15][c:16]1[n:17][c:18](-[c:27]2[c:28]([OH:33])[cH:29][cH:30][cH:31][cH:32]2)[n:19][c:20]2[cH:21][cH:22][c:23]([F:26])[cH:24][c:25]12.[Cl:41][CH2:42][Cl:43].[NH:1]1[CH2:2][CH:3]([NH:6][C:7]([O:8][CH:9]2[CH2:10][O:11][CH2:12][CH2:13]2)=[O:14])[CH2:4][CH2:5]1>>[N:1]1([c:16]2[n:17][c:18](-[c:27]3[c:28]([OH:33])[cH:29][cH:30][cH:31][cH:32]3)[n:19][c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][c:25]23)[CH2:2][CH:3]([NH:6][C:7]([O:8][CH:9]2[CH2:10][O:11][CH2:12][CH2:13]2)=[O:14])[CH2:4][CH2:5]1