4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine → N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-1,5-naphthyridin-1(2H)-yl)acetamide

反応式

[Br:16][c:17]1[c:18](-[c:23]2[n:24][cH:25][n:26][nH:27]2)[c:19]([NH2:22])[s:20][cH:21]1.[O:1]=[c:2]1[n:3]([CH2:12][C:13](=[O:14])[OH:15])[c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1>>[O:1]=[c:2]1[n:3]([CH2:12][C:13](=[O:15])[NH:22][c:19]2[c:18](-[c:23]3[n:24][cH:25][n:26][nH:27]3)[c:17]([Br:16])[cH:21][s:20]2)[c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1

参加物

反応物 2

HCID 596366864-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine

HCID 687824352-(2-oxo-1,5-naphthyridin-1(2H)-yl)acetic acid

生成物 1

HCID 59636685N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-1,5-naphthyridin-1(2H)-yl)acetamide

出典と根拠

ORDレコード: ord-7e4e0fa4bfc346bb97086390a6ab4072
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…