Dichloromethane → 3-{[3-(2-Chloro-6-fluoro-phenyl)-5-methyl-isoxazole-4-carbonyl]-amino}-piperidine-1-carboxylic acid methyl ester

反応式

[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:25][O:26][C:27](=[O:28])[N:29]1[CH2:30][CH:31]([NH2:35])[CH2:32][CH2:33][CH2:34]1.[CH3:36][N:37]([CH3:38])[c:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1.[Cl:45][CH2:46][Cl:47].[Cl:8][c:9]1[c:10](-[c:16]2[n:17][o:18][c:19]([CH3:24])[c:20]2[C:21](=[O:22])[Cl:23])[c:11]([F:15])[cH:12][cH:13][cH:14]1>>[Cl:8][c:9]1[c:10](-[c:16]2[n:17][o:18][c:19]([CH3:24])[c:20]2[C:21](=[O:22])[NH:35][CH:31]2[CH2:30][N:29]([C:27]([O:26][CH3:25])=[O:28])[CH2:34][CH2:33][CH2:32]2)[c:11]([F:15])[cH:12][cH:13][cH:14]1