2-Fluoropyridine-3-boronic acid → [7-(2-Fluoro-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-morpholin-4-yl-phenyl)-amine

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][O:21][CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12.[F:24][c:25]1[n:26][cH:27][cH:28][cH:29][c:30]1[B:31]([OH:32])[OH:33]>>[c:2]1(-[c:30]2[c:25]([F:24])[n:26][cH:27][cH:28][cH:29]2)[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][O:21][CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12

参加物

反応物 2

HCID 27832702-Fluoropyridine-3-boronic acid

HCID 54578326(7-Bromo-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(4-morpholin-4-yl-phenyl)-amine

生成物 1

HCID 66712042[7-(2-Fluoro-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-morpholin-4-yl-phenyl)-amine

出典と根拠

ORDレコード: ord-4362592ec1ac4e308db35754c46db911
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…