Hydroxide → {6-[5-(4-fluoro-3-trifluoromethyl-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid

反応式

[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][n:6]1[cH:7][cH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][c:17]3[n:18]([CH3:33])[n:19][c:20](-[c:22]4[cH:23][c:24]([C:29]([F:30])([F:31])[F:32])[c:25]([F:28])[cH:26][cH:27]4)[cH:21]3)[cH:13][c:14]12)=[O:34].[Li+:36].[OH-:35]>>[O:3]=[C:4]([CH2:5][n:6]1[cH:7][cH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][c:17]3[n:18]([CH3:33])[n:19][c:20](-[c:22]4[cH:23][c:24]([C:29]([F:30])([F:31])[F:32])[c:25]([F:28])[cH:26][cH:27]4)[cH:21]3)[cH:13][c:14]12)[OH:34]

参加物

反応物 3

HCID 961Hydroxide

HCID 28486Lithium ion

HCID 69282809{6-[5-(4-fluoro-3-trifluoromethyl-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl ester

生成物 1

HCID 69282796{6-[5-(4-fluoro-3-trifluoromethyl-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid

出典と根拠

ORDレコード: ord-e3c55639dda54cd38cf246df389f5bdc
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…