Hydrochloric Acid → (3RS,4RS)-4-(3-bromophenyl)-3-(naphthalen-2-ylmethoxy)-piperidine

反応式

[Br:1][c:2]1[cH:3][c:4]([CH:8]2[CH:9]([O:21][CH2:22][c:23]3[cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[cH:31][cH:32]3)[CH2:10][N:11]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1.[CH3:34][OH:35].[ClH:33]>>[Br:1][c:2]1[cH:3][c:4]([CH:8]2[CH:9]([O:21][CH2:22][c:23]3[cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[cH:31][cH:32]3)[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 54568307tert-butyl (3RS,4RS)-4-(3-bromophenyl)-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate

生成物 1

HCID 22128536(3RS,4RS)-4-(3-bromophenyl)-3-(naphthalen-2-ylmethoxy)-piperidine

出典と根拠

ORDレコード: ord-aac9d6a969f64504a2ff1632df6fdac5
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…