2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine → 1,3-Dimethyl-8-[2-(4-trifluoromethyl-phenyl)-ethyl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine

反応式

[CH3:1][c:2]1[n:3]([CH2:8][CH2:9][NH2:10])[cH:4][c:5]([CH3:7])[n:6]1.[F:11][C:12]([c:13]1[cH:14][cH:15][c:16]([CH2:19][CH2:20][CH:21]=[O:22])[cH:17][cH:18]1)([F:23])[F:24]>>[CH3:1][c:2]1[n:3]2[c:4]([c:5]([CH3:7])[n:6]1)[CH:21]([CH2:20][CH2:19][c:16]1[cH:15][cH:14][c:13]([C:12]([F:11])([F:23])[F:24])[cH:18][cH:17]1)[NH:10][CH2:9][CH2:8]2

参加物

反応物 2

HCID 184607002-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine

HCID 216838073-[4-(Trifluoromethyl)phenyl]propanal

生成物 1

HCID 667342311,3-Dimethyl-8-[2-(4-trifluoromethyl-phenyl)-ethyl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine

出典と根拠

ORDレコード: ord-c6f2f9789c2045c49c4663146f6bc662
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…