Toluene → 1,1-Dimethylethyl 4-[[3-[[6-(trifluoromethyl)-3-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxylate

HRID 1136971ノート

反応式

HRID 1136971 の反応式
[Br:22][c:23]1[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[n:27][cH:28]1.[C:33](=[O:34])([O-:35])[O-:36].[CH3:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[Cs+:37].[Cs+:38].[OH:1][c:2]1[cH:3][c:4]([CH:5]=[C:6]2[CH2:7][CH2:8][N:9]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10][CH2:11]2)[cH:19][cH:20][cH:21]1>>[O:1]([c:2]1[cH:3][c:4]([CH:5]=[C:6]2[CH2:7][CH2:8][N:9]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10][CH2:11]2)[cH:19][cH:20][cH:21]1)[c:23]1[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[n:27][cH:28]1

参加物

6

反応物 5

HCID 1140TolueneHCID 19660Carbonate IonHCID 104967Cesium cation2 回HCID 27611975-Bromo-2-(trifluoromethyl)pyridineHCID 53485958Tert-butyl 4-(3-hydroxybenzylidene)piperidine-1-carboxylate

生成物 1

HCID 668757901,1-Dimethylethyl 4-[[3-[[6-(trifluoromethyl)-3-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxylate

出典と根拠

ORDレコード
ord-b253116a775748a794ba40e7f2d39a48
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反応ノート

読み込み中…