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trans-2-Phenyl-1-cyclopropanecarbonyl chloride → (1R*,2R*)-N-{3-[4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-2-phenylcyclopropanecarboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | trans-2-Phenyl-1-cyclopropanecarbonyl chloride | HCID 13656 | — |
| 反応物 | 1-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine | HCID 21946031 | — |
| 生成物 | (1R*,2R*)-N-{3-[4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-2-phenylcyclopropanecarboxamide | HCID 59049849 | — |
反応手順
Using the method of Examples 78–92, trans-2-phenyl-1-cyclopropanecarbonyl chloride was reacted with 1-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired product. The observed accurate mass was 378.2298.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07098221B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-d63943723ec344abb2ab368b9531d738 |
| 出典メモ | uspto-grants-2006_08 |