Dichloromethane → Tert-butyl 1-(2-(2-hydroxyphenyl)quinazolin-4-yl)piperidin-4-ylcarbamate

反応式

[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[Cl:1][c:2]1[n:3][c:4](-[c:12]2[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[Cl:40][CH2:41][Cl:42].[NH:19]1[CH2:20][CH2:21][CH:22]([NH:25][C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH2:23][CH2:24]1>>[c:2]1([N:19]2[CH2:20][CH2:21][CH:22]([NH:25][C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH2:23][CH2:24]2)[n:3][c:4](-[c:12]2[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]2)[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12