2-Methylpyridine-4-boronic acid → 4-(azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(2-methyl-pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-amide

反応式

[CH3:26][c:27]1[n:28][cH:29][cH:30][c:31]([B:33]([OH:34])[OH:35])[cH:32]1.[N:1]1([C:5](=[O:6])[c:7]2[cH:8][n:9][n:10]([CH3:25])[c:11]2[C:12](=[O:13])[NH:14][c:15]2[cH:16][c:17]3[n:18]([cH:19][cH:20]2)[n:21][c:22]([Br:24])[n:23]3)[CH2:2][CH2:3][CH2:4]1>>[N:1]1([C:5](=[O:6])[c:7]2[cH:8][n:9][n:10]([CH3:25])[c:11]2[C:12](=[O:13])[NH:14][c:15]2[cH:16][c:17]3[n:18]([cH:19][cH:20]2)[n:21][c:22](-[c:31]2[cH:30][cH:29][n:28][c:27]([CH3:26])[cH:32]2)[n:23]3)[CH2:2][CH2:3][CH2:4]1

参加物

反応物 2

HCID 41926642-Methylpyridine-4-boronic acid

HCID 573782924-(azetidine-1-carbonyl)-N-(2-bromo-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-methyl-1H-pyrazole-5-carboxamide

生成物 1

HCID 573783884-(azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid [2-(2-methyl-pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-amide

出典と根拠

ORDレコード: ord-0af27956ae064b00a3eb88a4f2457c90
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…