Methanol → 4-(2-Cyano-1-hydroxyethyl)-4-methylpiperidine-1-carboxylic acid tert-butyl ester

反応式

[BH4-:20].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH3:14])([C:15]([CH2:16][C:17]#[N:18])=[O:19])[CH2:12][CH2:13]1.[CH3:22][OH:23].[Na+:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH3:14])([CH:15]([CH2:16][C:17]#[N:18])[OH:19])[CH2:12][CH2:13]1