Water → 6-chloro-2-pyrazin-2-yl-5-(2,4,6-trifluorophenyl)-N-(1,1,1-trifluoropropan-2-yl)pyrimidin-4-amine

反応式

[CH3:36][N:37]1[CH2:38][CH2:39][CH2:40][C:41]1=[O:42].[CH:32]([OH:33])([CH3:34])[CH3:35].[Cl:1][c:2]1[n:3][c:4](-[c:18]2[n:19][cH:20][cH:21][n:22][cH:23]2)[n:5][c:6]([Cl:17])[c:7]1-[c:8]1[c:9]([F:16])[cH:10][c:11]([F:15])[cH:12][c:13]1[F:14].[F:24][C:25]([CH:26]([CH3:27])[NH2:28])([F:29])[F:30].[OH2:31]>>[Cl:1][c:2]1[n:3][c:4](-[c:18]2[n:19][cH:20][cH:21][n:22][cH:23]2)[n:5][c:6]([NH:28][CH:26]([C:25]([F:24])([F:29])[F:30])[CH3:27])[c:7]1-[c:8]1[c:9]([F:16])[cH:10][c:11]([F:15])[cH:12][c:13]1[F:14]