1,4-Dioxane → 5-Chloro-4-[(4-chlorophenylthio)(2,5-difluorophenyl)methyl]-2-(3,4-dimethoxybenzylamino)pyridine

反応式

[CH3:26][O:27][c:28]1[cH:29][c:30]([CH2:31][NH2:32])[cH:33][cH:34][c:35]1[O:36][CH3:37].[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:25])[c:6]([CH:8]([c:9]2[c:10]([F:16])[cH:11][cH:12][c:13]([F:15])[cH:14]2)[S:17][c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[cH:7]1.[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1>>[c:2]1([NH:32][CH2:31][c:30]2[cH:29][c:28]([O:27][CH3:26])[c:35]([O:36][CH3:37])[cH:34][cH:33]2)[n:3][cH:4][c:5]([Cl:25])[c:6]([CH:8]([c:9]2[c:10]([F:16])[cH:11][cH:12][c:13]([F:15])[cH:14]2)[S:17][c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[cH:7]1

参加物

反応物 3

HCID 312751,4-Dioxane

HCID 79832Veratrylamine

HCID 231145672,5-Dichloro-4-[(4-chlorophenylthio)-(2,5-difluorophenyl)methyl]pyridine

生成物 1

HCID 231147075-Chloro-4-[(4-chlorophenylthio)(2,5-difluorophenyl)methyl]-2-(3,4-dimethoxybenzylamino)pyridine

出典と根拠

ORDレコード: ord-1d1b4e86a29d4659abc7ab475a2d9e73
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…