(3-(Trifluoromethyl)phenyl)hydrazine hydrochloride → HCID 1486556、化合物
反応式
Cl[C:2]1[CH:3]=[C:4]([N:8]2[C:12](=[O:13])[C:11]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)=[CH:10][N:9]2CC)[CH:5]=[CH:6][CH:7]=1.Cl.[F:24][C:25]([F:35])([F:34])C1C=C(NN)C=CC=1>CO>[Cl:20][C:16]1[CH:15]=[C:14]([C:11]2[C:12](=[O:13])[N:8]([C:4]3[CH:3]=[C:2]([C:25]([F:35])([F:34])[F:24])[CH:7]=[CH:6][CH:5]=3)[NH:9][CH:10]=2)[CH:19]=[CH:18][CH:17]=1参加物
4
実験手順
A mixture of 12 grams of the 3-chloroatropic acid, methyl ester (prepared in Example 9 above), 13 grams 3-(trifluoromethyl)phenylhydrazine hydrochloride and 100 ml. methanol was refluxed overnight to yield 4.6 grams of 4-(3-chlorophenyl)-1-(α,α,α-trifluoro-3-tolyl)-3-pyrazolin-5-one, m.p. 190°-192° C.