4-Nitro-3-(trifluoromethyl)aniline → HCID 22818468、化合物
反応式
[C@@H:1]1([C:10](Cl)=[O:11])[CH2:6][CH2:5][CH2:4][CH2:3][C@H:2]1[C:7](Cl)=[O:8].[F:13][C:14]([F:26])([F:25])[C:15]1[CH:16]=[C:17]([CH:19]=[CH:20][C:21]=1[N+:22]([O-:24])=[O:23])[NH2:18]>C1C=CC=CC=1>[F:13][C:14]([F:25])([F:26])[C:15]1[CH:16]=[C:17]([NH:18][C:10]([C@@H:1]2[CH2:6][CH2:5][CH2:4][CH2:3][C@H:2]2[C:7]([NH:18][C:17]2[CH:19]=[CH:20][C:21]([N+:22]([O-:24])=[O:23])=[C:15]([C:14]([F:13])([F:25])[F:26])[CH:16]=2)=[O:8])=[O:11])[CH:19]=[CH:20][C:21]=1[N+:22]([O-:24])=[O:23]参加物
4
実験手順
Reflux a mixture of 16.73 g (0.08 moles) of trans-1,2-cyclohexane dicarboxylic acid chloride and 32.96 g (0.16 moles) of 3-trifluoromethyl-4-nitroaniline in 250 ml of benzene for 1.5 hours. Isolate the solid product of this example by filtering, washing well with hot benzene followed by ether and obtain analytically pure material by recrystallization from benzenemethanol, mp 249.5°-251° C. (dec.).