Potassium Carbonate → 2-(1,4-BENZODIOXAN-2YL)-METHYLENE-BENZIMIDAZOLE

HRID 1155294ノート

反応式

HRID 1155294 の反応式
Cl.[O:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[O:5][CH2:4][CH:3]1[CH2:12][C:13]1[NH:14][C:15]2[CH:21]=[CH:20][CH:19]=[CH:18][C:16]=2[N:17]=1.C(=O)([O-])[O-].[K+].[K+]>CCOCC>[O:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[O:5][CH2:4][CH:3]1[CH2:12][C:13]1[NH:17][C:16]2[CH:18]=[CH:19][CH:20]=[CH:21][C:15]=2[N:14]=1

参加物

4

反応物 2

HCID 11430Potassium CarbonateHCID 12761781HCID 12761781、化合物

生成物 1

HCID 127617802-(1,4-BENZODIOXAN-2YL)-METHYLENE-BENZIMIDAZOLE

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

2-(1,4-benzodioxan-2-ylmethyl)benzimidazole hydrochloride (1.0 g) suspended in 50 ml of ether is stirred with excess dilute aqueous potassium carbonate solution until the salt is completely dissolved. The organic layer is then separated, washed twice with water, dried over magnesium sulfate and evaporated to yield 2-(1,4-benzodioxan-2-ylmethyl)benzimidazole.

後処理

  1. dissolutionis completely dissolved
  2. customThe organic layer is then separated
  3. washwashed twice with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

出典と根拠

ORDレコード
ord-54f10b772d3b4f11b68bee647f30b9b3
出典データセット
uspto-grants-1981_11
特許番号
US04301171

反応ノート

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