Pyridine, 2-(4-methoxyphenoxy)-5-(trifluoromethyl)- → 4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol

HRID 1155474

反応式

HRID 1155474 の反応式
C[O:2][C:3]1[CH:19]=[CH:18][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][N:9]=2)=[CH:5][CH:4]=1.Cl.N1C=CC=CC=1>O.Cl>[OH:2][C:3]1[CH:19]=[CH:18][C:6]([O:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:15])[F:16])=[CH:10][N:9]=2)=[CH:5][CH:4]=1

参加物

5

反応物 2

HCID 155242Pyridine, 2-(4-methoxyphenoxy)-5-(trifluoromethyl)-HCID 10176127Pyridinium chloride

生成物 1

HCID 1552414-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 962Water溶媒

実験手順

The product from (c) (1.7 g) and excess of pyridine hydrochloride were heated together for 8 hours at 180° C. The mixture was cooled, diluted with water and 2-molar hydrochloric acid, and extracted with ether. The extracts were dried and evaporated to yield an oil identified as the required hydroxy compound.

後処理

  1. temperatureThe mixture was cooled
  2. extractionextracted with ether
  3. customThe extracts were dried
  4. customevaporated
  5. customto yield an oil

出典と根拠

ORDレコード
ord-b2b93f581afd4ba08de951bf7d3c848f
出典データセット
uspto-grants-1981_11
特許番号
US04302242

関連ノート

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