Phosgene → 2-Chloro-3-pyridinesulfonylisocyanate

HRID 1155940ノート

反応式

HRID 1155940 の反応式
[Cl:1][C:2]1[C:7]([S:8]([NH:11][C:12](=[O:18])NCCCC)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.C(Cl)(Cl)=O>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[C:7]([S:8]([N:11]=[C:12]=[O:18])(=[O:9])=[O:10])=[CH:6][CH:5]=[CH:4][N:3]=1

参加物

4

反応物 2

HCID 6371PhosgeneHCID 12383441HCID 12383441、化合物

生成物 1

HCID 130384352-Chloro-3-pyridinesulfonylisocyanate

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

To 125 ml of dry xylene was added with stirring 20.7 g of 2-chloro-N-(butylcarbamoyl)-3-pyridinesulfonamide. This solution was heated to reflux, and phosgene added until no further uptake of this gas was observed. It was then cooled, filtered and the solvent was removed in vacuo to yield 2-chloro-3-pyridinesulfonylisocyanate as an oil bp 108°-110° (0.7 mm Hg). This product showed a sharp absorption peak in the infrared region at 2220 cm-1.

後処理

  1. temperatureThis solution was heated
  2. temperatureto reflux
  3. temperatureIt was then cooled
  4. filtrationfiltered
  5. customthe solvent was removed in vacuo

出典と根拠

ORDレコード
ord-635ba1a774914d31bb6bb41e0c9f243b
出典データセット
uspto-grants-1982_06
特許番号
US04333760

反応ノート

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