関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Benzoyl chloride | HCID 7412 | — |
| 反応物 | Ethyl Acrylate | HCID 8821 | — |
| 反応物 | Benzenemethanamine, N,N-diethyl- | HCID 61211 | — |
| 反応物 | 3-Chloro-N,N-dimethylbenzenemethanamine | HCID 12617447 | — |
| 触媒 | palladium(II) acetate | HCID 167845 | — |
| 溶媒 | P-Xylene | HCID 7809 | — |
| 生成物 | Ethyl 3-phenylprop-2-enoate | HCID 7649 | — |
| 生成物 | Benzenemethanamine, N,N-diethyl- | HCID 61211 | — |
反応手順
Ethyl cinnamate is prepared by the procedures described above, using different bases and the following reactants: 2.24 mg (10-5 mols) of palladium acetate, 5.77 ml (50 millimols) of benzoyl chloride, 5.42 ml (50 millimols) of ethyl acrylate and 50 millimols of N-benzyldiethylamine or N-(3-chlorobenzyl)-dimethylamine, in 100 ml of p-xylene. The reaction mixture is stirred for 4 hours at 130° C. Ethyl cinnamate is obtained in a yield of 67% of theory if N-benzyldiethylamine is used, and a yield of 56% of theory if N-(3-chlorobenzyl)-dimethylamine is used.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04335054 |
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| 出典データセット | uspto-grants-1982_06 |
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| ORD ID | ord-7496f35003b84bafb24159c4480260bc |
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| 出典メモ | uspto-grants-1982_06 |
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