Ammonia → 1,5,6,7-Tetrahydro-4H-indol-4-one
反応式
C(O[CH:4]1[CH2:12][C:11]2[C:10](=O)[CH2:9][CH2:8][CH2:7][C:6]=2[O:5]1)C.[NH3:14]>>[O:5]=[C:6]1[CH2:7][CH2:8][CH2:9][C:10]2[NH:14][CH:4]=[CH:12][C:11]1=2参加物
3
反応条件
- 温度
- 100 °C
実験手順
96.5 mg of 2-ethoxy-4-oxo-2,3,4,5,6,7-hexahydrocoumarone and 1.5 ml of 28% aqueous ammonia were admixed in a glass tube which was sealed and heated at 100° C. for 14 hours. The reaction mixture was treated in the same manner as Example 11 to give 38.4 mg of 4-oxo-4,5,6,7-tetrahydroindole (yield 54%).
後処理
- customwhich was sealed
- additionThe reaction mixture was treated in the same manner as Example 11
出典と根拠
- ORDレコード
- ord-116ca53683b0484f8e251164ad5c75b5
- 出典データセット
- uspto-grants-1982_06
- 特許番号
- US04336202
反応ノート
読み込み中…