Ammonium Hydroxide → 5-(4-tert-BUTYLPHENYL)-3-ISOXAZOLECARBOXAMIDE
反応式
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[O:15][N:14]=[C:13]([C:16]([O:18]CC)=O)[CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[OH-].[NH4+:22]>O>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[O:15][N:14]=[C:13]([C:16]([NH2:22])=[O:18])[CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]参加物
4
実験手順
Ethyl 5-(4-tert-butylphenyl)-3-isoxazolecarboxylate (25 grams) was mixed with 1 liter of concentrated ammonium hydroxide, and the reaction mixture stirred overnight (about 18 hours) at room temperature. The reaction mixture was then poured into 1 liter of water. The product precipitated and was separated by filtration, yield, 34 grams. The structure of the product was confirmed by NMR.
後処理
- customThe product precipitated
- customwas separated by filtration
- customyield
出典と根拠
- ORDレコード
- ord-310fee898a5f45d29ad52811917a6b0e
- 出典データセット
- uspto-grants-1982_06
- 特許番号
- US04336264
反応ノート
読み込み中…