HCID 20534502、化合物 → [(5,6-dichloro-3-oxo-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]acetic acid
反応式
ClC1C(Cl)=C(CC([O-])=O)C=C2C=1C1C(CC)(C2)CCC(=O)C=1.[Cl:23][C:24]1[C:36]([Cl:37])=[C:35]([O:38][CH2:39][C:40]([O:42]C(C)(C)C)=[O:41])[CH:34]=[C:33]2[C:25]=1[C:26]1[C:31]([CH2:47][CH2:48][CH3:49])([CH2:32]2)[CH2:30][CH2:29][C:28](=[O:50])[CH:27]=1>>[Cl:23][C:24]1[C:36]([Cl:37])=[C:35]([O:38][CH2:39][C:40]([OH:42])=[O:41])[CH:34]=[C:33]2[C:25]=1[C:26]1[C:31]([CH2:47][CH2:48][CH3:49])([CH2:32]2)[CH2:30][CH2:29][C:28](=[O:50])[CH:27]=1参加物
3
実験手順
Carrying out a reaction as described in Example 53, Step B, except that the tert.-butyl [(5,6-dichloro-9a-ethyl-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)acetate is replaced by an equimolar amount of tert.-butyl [(5,6-dichloro-3-oxo-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]-acetate, thereby is obtained [(5,6-dichloro-3-oxo-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]acetic acid.
後処理
- customCarrying out a reaction
出典と根拠
- ORDレコード