Hydrochloric Acid → HCID 68423386、化合物

HRID 1157180

反応式

HRID 1157180 の反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]3[N:26]=[CH:25][CH:24]=[CH:23][N:22]=3)=[CH:17][CH:16]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:27]>>[ClH:27].[NH:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]2[CH:16]=[CH:17][C:18]([C:21]3[N:22]=[CH:23][CH:24]=[CH:25][N:26]=3)=[CH:19][CH:20]=2)[CH2:12][CH2:13]1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 589851534-(4-Pyrimidin-2-yl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester

生成物 1

HCID 68423386HCID 68423386、化合物

実験手順

Stirred 4-(4-Pyrimidin-2-yl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester (110 mg, 0.310 mmol) in 4M HCl (20 ml) at room temperature for 1 hour. Solvent was evaporated yielding desired product piperidin-4-yl-(4-pyrimidin-2-yl-phenyl)-amine, hydrochloride (114 mg).

後処理

  1. customSolvent was evaporated

出典と根拠

ORDレコード
ord-a069523144e74a46bc0076cc7a5df77f
出典データセット
uspto-grants-2010_10
特許番号
US07807672B2

関連ノート

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