1-Octen-3-one → 1-[4-(3-Phenylpropyl)piperidin-1-yl]octan-3-one

HRID 1157694ノート

反応式

HRID 1157694 の反応式
[C:1]1([CH2:7][CH2:8][CH2:9][CH:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:16]=[CH:17][C:18](=[O:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>C(O)C>[C:1]1([CH2:7][CH2:8][CH2:9][CH:10]2[CH2:11][CH2:12][N:13]([CH2:16][CH2:17][C:18](=[O:24])[CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH2:14][CH2:15]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 613461-Octen-3-oneHCID 876784-(3-Phenylpropyl)piperidine

生成物 1

HCID 115372371-[4-(3-Phenylpropyl)piperidin-1-yl]octan-3-one

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

1 equivalent of 4-(3-phenylpropyl)piperidine was reacted with 1 equivalent of 1-octen-3-one in ethanol, at room temperature. The product was worked up and purified on a column of silica. The results of the NMR and mass spectrometry analyses were in accordance with the expected structure.

後処理

  1. custompurified on a column of silica
  2. customThe results of the NMR and mass spectrometry analyses

出典と根拠

ORDレコード
ord-b4a31479269c432a92e73378c7119399
出典データセット
uspto-grants-2010_10
特許番号
US07807695B2

反応ノート

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