Hydrochloric Acid → Hydrochloric Acid

反応式

[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][NH:16][C:17](=[O:18])[c:19]2[c:20]([O:26][c:27]3[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]3)[n:21][cH:22][c:23]([F:25])[cH:24]2)[cH:13][cH:14]1)([CH3:5])([CH3:6])[CH3:34].[CH3:36][OH:37].[ClH:35]>>[ClH:35].[NH2:7][CH2:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][NH:16][C:17](=[O:18])[c:19]2[c:20]([O:26][c:27]3[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]3)[n:21][cH:22][c:23]([F:25])[cH:24]2)[cH:13][cH:14]1

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 20738636[4-({[5-Fluoro-2-(4-fluoro-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-benzyl]-carbamic acid tert-butyl ester

生成物 2

HCID 313Hydrochloric Acid

HCID 20738631N-[[4-(aminomethyl)phenyl]methyl]-5-fluoro-2-(4-fluorophenoxy)pyridine-3-carboxamide

出典と根拠

ORDレコード: ord-7b6cc2c68bae45c485ef82647fb917b7
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…