化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 7-Tert-butyl-chroman-4-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-[2-(3-Tert-butyl-phenoxy)-ethyl]-[1,3]dioxane | HCID 59548552 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 7-Tert-butyl-chroman-4-ol | HCID 59548526 | — |
反応手順
The intermediate from step A was dissolved in 20 ml tetrahydrofuran. Concentrated hydrochloric acid (20 mL) was added, and the reaction mixture was stirred at ambient temperature for 4 hours, diluted with diethyl ether and washed with water. The isolated organic layer was dried with magnesium sulfate, filtered and the solvent removed under reduced pressure to give 2.87 g of crude 7-tert-butyl-chroman-4-ol which was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07812019B2 |
| 出典データセット | uspto-grants-2010_10 |
| ORD ID | ord-d25c8a5b32e84a68a77b3e7aee1f0cba |
| 出典メモ | uspto-grants-2010_10 |