5-(Methylsulphonyl)pyridine-3-boronic acid → 4-Fluoro-1-(2-fluoro-5-(5-(methylsulfonyl)pyridin-3-yl)phenyl)-1-(2-methylpyridin-4-yl)-1H-isoindol-3-amine

HRID 115946

反応式

[Br:1][c:2]1[cH:3][cH:4][c:5]([F:26])[c:6]([C:8]2([c:19]3[cH:20][c:21]([CH3:25])[n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1.[CH3:27][S:28](=[O:29])(=[O:30])[c:31]1[cH:32][c:33]([B:37]([OH:38])[OH:39])[cH:34][n:35][cH:36]1>>[c:2]1(-[c:33]2[cH:32][c:31]([S:28]([CH3:27])(=[O:29])=[O:30])[cH:36][n:35][cH:34]2)[cH:3][cH:4][c:5]([F:26])[c:6]([C:8]2([c:19]3[cH:20][c:21]([CH3:25])[n:22][cH:23][cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1