Hydrochloric Acid → 1-phenyl-2-chloro-2-methylpropane

HRID 1160701

反応式

HRID 1160701 の反応式
[C:1]1([CH2:7][C:8](O)([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:12]>>[C:1]1([CH2:7][C:8]([Cl:12])([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 75312-Methyl-1-phenyl-2-propanol

生成物 1

HCID 2963571-phenyl-2-chloro-2-methylpropane

実験手順

A mixture of 5.92 g (40 mmoles) of 1-phenyl-2-hydroxy-2-methylpropane and 50 mL conc. hydrochloric acid was stirred at ice bath temperature for 1 h and at RT for 3 h. The reaction mixture was then extracted with ether. The organic layer was dried over MgSO4. Solvent removal gave 1-phenyl-2-chloro-2-methylpropane.

後処理

  1. waitat RT for 3 h
  2. extractionThe reaction mixture was then extracted with ether
  3. dry with materialThe organic layer was dried over MgSO4
  4. customSolvent removal

出典と根拠

ORDレコード
ord-b026e2ba81fa449ba4434f45639c3327
出典データセット
uspto-grants-2010_10
特許番号
US07816534B2

関連ノート

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