Hydrazine → 6-(Propan-2-yl)-4,5-dihydropyridazin-3(2H)-one
反応式
[CH3:1][CH:2]([CH3:10])[C:3](=O)[CH2:4][CH2:5][C:6](O)=[O:7].[NH2:11][NH2:12]>C(O)C>[CH:2]([C:3]1[CH2:4][CH2:5][C:6](=[O:7])[NH:11][N:12]=1)([CH3:10])[CH3:1]参加物
4
実験手順
5-Methyl-4-oxohexanoic acid (3.60 g, 25.0 mmol) and anhydrous hydrazine (0.80 g, 26.0 mmol) were heated for 3 hours in ethanol (36.0 ml) under stirring. After the reaction solution was concentrated under reduced pressure, hexane was added to the residues to precipitate crystals, and the crystals were collected by filtration to give 4,5-dihydro-6-isopropyl-3 (2H)-pyridazinone as crystals. The yield was 3.10 g.
後処理
- concentrationAfter the reaction solution was concentrated under reduced pressure, hexane
- additionwas added to the residues
- customto precipitate crystals
- filtrationthe crystals were collected by filtration
出典と根拠
- ORDレコード
- ord-3dbb2e47ec2d450cb00e0d1ef5831cda
- 出典データセット
- uspto-grants-2010_10
- 特許番号
- US07816526B2
反応ノート
読み込み中…