3-[3-(4-Methoxy-phenoxymethyl)-[1,2,4]oxadiazol-5-ylmethyl]-benzoic acid ethyl ester → 3-(3-Hydroxymethyl-[1,2,4]oxadiazol-5-ylmethyl)-benzoic acid ethyl ester
反応式
C(OC(=O)C1C=CC(CC2ON=C(CO)N=2)=CC=1)C.[CH2:20]([O:22][C:23](=[O:46])[C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH2:30][C:31]2[O:35][N:34]=[C:33]([CH2:36][O:37]C3C=CC(OC)=CC=3)[N:32]=2)[CH:25]=1)[CH3:21]>>[CH2:20]([O:22][C:23](=[O:46])[C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH2:30][C:31]2[O:35][N:34]=[C:33]([CH2:36][OH:37])[N:32]=2)[CH:25]=1)[CH3:21]参加物
3
実験手順
The title compound is prepared essentially as described for 4-(3-hydroxymethyl-[1,2,4]oxadiazol-5-ylmethyl)-benzoic acid ethyl ester, employing 3-[3-(4-methoxy-phenoxymethyl)-[1,2,4]oxadiazol-5-ylmethyl]-benzoic acid ethyl ester (81%). LC-MS (m/e): 263 (M+1).
出典と根拠
- ORDレコード
- ord-c564fcb6fce3488bae2706aeaac72653
- 出典データセット
- uspto-grants-2010_10
- 特許番号
- US07816523B2
反応ノート
読み込み中…