Water → HCID 178423997、化合物
反応式
[NH2:1][C:2]1[N:7]=[C:6](Cl)[C:5]([CH:9]=[O:10])=[C:4]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][C:12]=2[CH3:18])[N:3]=1.[S-2:19].[Na+].[Na+].O>CN(C=O)C>[NH2:1][C:2]1[N:3]=[C:4]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][C:12]=2[CH3:18])[C:5]([CH:9]=[O:10])=[C:6]([SH:19])[N:7]=1参加物
5
実験手順
2-Amino-4-chloro-6-(2,4-dimethylphenyl)-pyrimidine-5-carbaldehyde was added to a suspension of sodium sulphide (5 eq.) in DMF and the mixture stirred for ˜60 mins, to give a yellow suspension. The suspension was poured into water, and the solution filtered. The filtrate was acidified with acetic acid, to give a yellow precipitate. The solids were removed by filtration and washed with water and hexane, dried in vacuo, to give a yellow powder.
後処理
- customto give a yellow suspension
- filtrationthe solution filtered
- customto give a yellow precipitate
- customThe solids were removed by filtration
- washwashed with water and hexane
- customdried in vacuo
- customto give a yellow powder
出典と根拠
- ORDレコード
- ord-bc26fe5ae62741bc936b9b511aac1bb3
- 出典データセット
- uspto-grants-2010_10
- 特許番号
- US07820658B2
反応ノート
読み込み中…