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Ethyl 3-phenylprop-2-enoate → Ethyl 1-benzyl-4-phenylpyrrolidine-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 3-phenylprop-2-enoate | HCID 7649 | — |
| 反応物 | Benzyl(methoxymethyl)((trimethylsilyl)methyl)amine | HCID 353442 | — |
| 生成物 | Ethyl 1-benzyl-4-phenylpyrrolidine-3-carboxylate | HCID 12922290 | — |
反応手順
103.1 In analogy to example 101.1 ethyl cinnamate and N-benzyl-N-(methoxymethyl)tri-methylsilylmethylamine (CAS 93102-05-7) were reacted to give (3RS,4SR)-1-benzyl-4-phenyl-pyrrolidine-3-carboxylic acid ethyl ester. Light yellow liquid. MS 310.1 ([M+H]+)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07820699B2 |
| 出典データセット | uspto-grants-2010_10 |
| ORD ID | ord-60f35d5749dd4718a1f89243061792a6 |
| 出典メモ | uspto-grants-2010_10 |