Potassium Hydroxide → 2-(o-Tolylthio)-6-(1-propenyl)phenol
反応式
[C:1]1([CH3:18])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH2:14][CH:15]=[CH2:16])[C:9]=1[OH:17].[OH-].[K+]>CO>[C:1]1([CH3:18])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]=[CH:15][CH3:16])[C:9]=1[OH:17]参加物
4
反応条件
- 温度
- 110 °C
実験手順
A mixture of 2-(o-tolylthio)-6-allylphenol (24 g) and potassium hydroxide (32 g) in methanol (100 ml) was stirred at 110° C. Methanol was distilled off from the mixture under ordinal pressure, and the mixture was stirred at 100° C. for an hour. The reaction mixture was cooled, acidified with conc. hydrochloric acid and extracted with diethyl ether. The extract was washed with water, dried and evaporated under reduced pressure to give oily 2-(o-tolylthio)-6-(1-propenyl)phenol (24.3 g).