Glyoxylic Acid → HCID 178521512、化合物

HRID 1164732

反応式

HRID 1164732 の反応式
[C:1]([OH:5])(=O)[CH:2]=[O:3].Cl.[Cl:7][C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[NH:15][NH2:16]>Cl.O>[Cl:7][C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[NH:15][N:16]=[C:1]([OH:5])[CH:2]=[O:3]

参加物

5

反応物 2

HCID 760Glyoxylic AcidHCID 2723905(2,4-Dichlorophenyl)hydrazine monohydrochloride

生成物 1

HCID 178521512HCID 178521512、化合物収率 69%

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid溶媒HCID 962Water溶媒2 回

実験手順

In a manner similar to that disclosed by HO House, et al (Organic Synthesis, Vol V, 258-263) the reaction of 3.4 g (0.046 mole) of glyoxylic acid in 40 mL of 2.5 N hydrochloric acid and 60 mL of water with a solution of 9.8 g (0.046 mole) of 2,4-dichlorophenylhydrazine hydrochloride in 30 mL of water produced 7.4 g of 2-oxoacetic acid 2,4-dichlorophenylhydrazone as a solid (m.p. 160° C., dec.).

後処理

  1. customIn a manner similar to that disclosed by HO House, et al (Organic Synthesis, Vol V, 258-263)

出典と根拠

ORDレコード
ord-bdaffcab6cc541bbbd16baa0b1ae320b
出典データセット
uspto-grants-1990_03
特許番号
US04906287

関連ノート

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