Aluminum(III) Chloride → HCID 178454735、化合物
反応式
[OH:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH3:11][CH:12]([CH2:16][C:17]([O:19]C)=[O:18])[C:13](Cl)=[O:14].[Cl-].[Al+3].[Cl-].[Cl-]>C(=S)=S>[C:17]([CH2:16][CH:12]([CH3:11])[C:13]([C:8]1[CH:9]=[CH:10][C:4]2[N:3]=[C:2]([OH:1])[NH:6][C:5]=2[CH:7]=1)=[O:14])([OH:19])=[O:18]参加物
5
実験手順
Carbon disulfide (90 ml), 2-hydroxybenzimidazole (4.1 g) and 2-methyl-3-carbomethoxy propionyl chloride (5 g) are added to aluminum chloride (20.3 g) under nitrogen. The resulting mixture is refluxed for about 45 hours, quenched with ice cold 6N HCl and the acidic mixture filtered. The filtered solid is washed with water and dried in vacuo, affording the desired product as a solid, M.P. 223° C. (dec).
後処理
- temperatureThe resulting mixture is refluxed for about 45 hours
- customquenched with ice cold 6N HCl
- filtrationthe acidic mixture filtered
- washThe filtered solid is washed with water
- customdried in vacuo
出典と根拠
- ORDレコード
- ord-8307db374afe4216886b389ebf9ee85c
- 出典データセット
- uspto-grants-1990_03
- 特許番号
- US04906630
反応ノート
読み込み中…